Head of Research and Development

Насловна › Пребарај › Head of Research and Development

Росоман

Рок за пријавување: 17.11.2024

Синцеритас АД Скопје
Адреса: Ул.Никола Кљусев бр.11, 1000 Скопје

Head of Research and Development

At SINCERITAS, we cultivate and process pharmaceutical-grade cannabis into medicinal products to improve patient health and provide relief. Offering cutting-edge solutions for numerous medical needs, we strive to meet every client’s unique requests by tailor-making each product.

We are a team of experienced science professionals that use industry-standard practices in agricultural and pharmaceutical techniques to manufacture high-quality medicinal cannabis products consistently and reliably. Our products are developed to retain all of the plant’s essential components and ensure a maximum medicinal effect, particularly in patients with rare and difficult-to-treat conditions.

Through ongoing scientific research and development, we aim to unlock the full therapeutic potential of cannabis, opening the doors to new and revolutionary medical treatments.

Sinceritas is made up of talented diverse team of over 60 employees who deliver innovative solutions that add value across a variety of Business Service functions. Our company culture is build on three pillars: Science.Progress.Trust

SINCERITAS offers premium workspace at our facility in Rosoman and administrative office in Skopje.

The Head of Research and Development will be responsible for developing innovative new processes, products, and other new technologies. The scope of work will include new method development, analytical validation, and production scale up for development and production of various new cannabis-based clinical products.

Responsibilities:

Method development for separation and purification of cannabinoids and other cannabis-based compounds
Lead scale-up from development to production quantities, in collaboration with plant production personnel
Assist in the development of new drug product formulations and drug-delivery technologies
Develop manufacturing instructions, scale up batches, and transfer processes into manufacturing
Design and perform method validations for new products, methods, and equipment
Work with the Quality Control department to perform necessary analytical testing of API, intermediates, raw materials and excipients as required for preparation and filing of regulatory documents
Review and establish specifications for novel products and processes
Provide investigational or summary reports on an as needed basis
Perform routine calibration and maintenance of equipment and daily quality control testing of analytical and /or preparative methods
Provide cost and man-hour estimates associated with R&D project proposals
Plan, coordinate, and oversee laboratory analyses for compliance actions, emergency response, site studies, health and safety studies, investigations, and remediation
Design and implement stability studies, degradation evaluation experiments; supervise technical staff
Liaison role between the company and the partner scientific institutions
Involved in IMS (Integrated Management System)
Other responsibilities in relation with candidate’s qualifications and skills.

Qualifications:

PhD in chemistry, biochemistry, pharmaceutical sciences, PhD
Minimum of 5 years of experience with preparative and analytical HPLC, and other preparative purification techniques
Proven experience in method development/validation in the pharmaceutical industry
Proven experience with separation and purification of compounds for drug API and/or drug product development
Excellent working knowledge of GMP practices, standard operating procedures, and master batch records
Excellent knowledge of drug formulation
Must have the proven ability to organize and prioritize work for efficient operations
Must be able to work cross-functionally
Excellent attention to detail is required

What we offer:

By investing in new development capabilities, state-of-the-art manufacturing facility, and partnerships we have the opportunity to shape the future of SINCERITAS and give more patients access to affordable, high-quality medicines - sustainably. Our dynamism and entrepreneurial spirit are driven by an open, collaborative culture, supported by our talented and ambitious colleagues who, in return for the use of their skills, experience an agile and collegial environment with impactful, flexible careers in which diversity is welcome and personal development is encouraged!

In addition to a basic salary in line with market, we offer:

1. Organized transport from Skopje to Rosoman

2. Provided meal for all the employees who are performing their job in Rosoman

3. Collective insurance for all the employees

Additional information: Candidates who meet the above conditions can send their CVs via Fast Apply.